Delta E is used to set quantitative Tolerance boundaries for color reproduction, such as a maximum acceptable difference like ΔE<2.0. This numerical threshold guides quality control by allowing or rejecting printed samples based on their deviation from the target color, ensuring consistency for brand colors.

ΔE00​ is the preferred standard (recommended by ISO) because it is the most perceptually uniform version of the metric. Unlike older formulas like ΔE76​, ΔE00​ includes corrections that better model how the human eye perceives differences in various hues, lightness, and chroma. This ensures that the measured color difference number accurately reflects the severity of the visual difference.