LPI plays a fundamental role in the Screening process, as it determines how continuous-tone images are converted into printable halftone dots. Choosing an inappropriate LPI can lead to errors such as Moire (if the Screen Angle is incorrect) or the loss of fine details in highlight and shadow areas.

LPI must be commensurate with the CTP device's capability, as the device laser's ability to create sufficient clarity for the accurate and stable formation of halftone dot cells is a technical limitation. Setting the LPI higher than the CTP device's capability causes the dot clarity to decrease, and the final visual print quality suffers severely. This synchronization is a key part of the Resolution Chain strategy.